Nexgard vs. Frontline: Which Is The Best Choice For Your Dog?

By Team Pawviva

Key Takeaways

  1. Type of Medication: Nexgard is an oral medication while Frontline is topical.
  2. Efficacy: Both are effective but have slightly different scopes of protection.
  3. Age and Weight Limitations: Each has its own restrictions based on your dog's age and weight.
  4. Cost and Availability: Available at affordable rates with free shipping through Pawviva.
  5. Ease of Administration: Oral vs. topical application—what's easier for you and your dog?

Choosing between Nexgard and Frontline for your dog's flea and tick prevention is crucial. This guide will take you through an in-depth comparison of Nexgard vs. Frontline to help you make the best decision for your furry friend's needs.

Table of Contents

  1. Introduction
  2. Types of Medication
  3. Scope of Protection
  4. Age and Weight Limitations
  5. Ease of Administration
  6. Cost and Availability
  7. FAQs
  8. Conclusion


The question of Nexgard vs. Frontline is a common dilemma for dog owners. Both brands are highly reputable and offer effective solutions for flea and tick prevention. But how do you choose the one that’s right for your pet? This article will break down everything you need to know.

Types of Medication


  • Form: Oral chewable tablet
  • Active Ingredient: Afoxolaner


  • Form: Topical solution
  • Active Ingredients: Fipronil, (S)-methoprene

Scope of Protection


  • Fleas
  • Ticks (Black-legged tick, American dog tick, and Brown dog tick)
  • Prevents Lyme disease


  • Fleas
  • Flea larvae
  • Ticks (Black-legged tick, American dog tick, and Brown dog tick)
  • Lice
  • Mites (some versions)

Age and Weight Limitations


  • Age: 8 weeks and older
  • Weight: 4 pounds and over


  • Age: 8 weeks and older for Frontline Plus, 12 weeks and older for Frontline Gold
  • Weight: No lower limit specified

Ease of Administration


  • Simply offer the chewable as a treat or with food.


  • Applied topically between the shoulder blades.

Cost and Availability

Both Nexgard and Frontline are conveniently available at Pawviva, offering trusted brands without the added cost of a vet visit. Plus, you can take advantage of our free shipping to make your purchase even more affordable.


  1. How soon do these treatments start working?

    • Nexgard: Within 24 hours
    • Frontline: Within 30 minutes for fleas, 24 hours for ticks
  2. Are there any side effects?

    • Both treatments are generally well-tolerated but can have some side effects. Always read the label.
  3. How often should I administer these treatments?

    • Nexgard: Monthly
    • Frontline: Monthly


When it comes to Nexgard vs. Frontline, the best choice will depend on your dog's specific needs and your own preferences for administration. Both offer strong protection against common parasites, but they do have subtle differences that might make one a better fit than the other. With affordable options and free shipping from Pawviva, protecting your dog has never been easier or more convenient.

Frequently asked questions